The notable NFL injuries during Thanksgiving weekend included two young quarterbacks and Raiders top wideout Amari Cooper. Here's a rundown of the week's biggest injuries.
1 of 18
Terron Armstead, OT, Saints
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The Saints fell to the Rams, and their offensive line also took a hit when Armstead left in the second half with a hamstring injury. His status is unknown.
2 of 18
Connor Barwin, LB, Rams
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Barwin left Sunday's game against New Orleans with an arm injury and was later ruled out.
3 of 18
C.J. Beathard, QB, 49ers
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Beathard suffered a lower leg injury against Seattle on Sunday, allowing midseason acquisition Jimmy Garoppolo to take the field. The 49ers are hopeful the injury is a bruise, but Garoppolo could replace Beathard next week in any event.
4 of 18
Amari Cooper, WR, Raiders
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Having already lost Michael Crabtree to a fight, the Raiders later lost Cooper to a concussion on Sunday. They still managed to beat the Broncos.
5 of 18
Marquise Goodwin, WR, 49ers
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The speedy Goodwin left Sunday's game with a foot injury in the third quarter and didn't return.
6 of 18
Ryan Kelly, C, Colts
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Kelly has been familiar to the trainer's table this season and was injured again on Sunday, suffering a concussion.
7 of 18
Paxton Lynch, QB, Broncos
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Lynch missed the start of the season due to a shoulder injury, and was knocked out of his first start of the season due to an ankle injury. If he didn't have bad luck, he'd have no luck at all.
8 of 18
Doug Martin, RB, Buccaneers
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Tampa Bay's starting running back left Sunday's game with a concussion, missing the second half.
9 of 18
Rashaan Melvin, CB, Colts
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Melvin left in the first half against the Titans with a hand injury. He was ruled out at halftime.
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Playing in his first game back from foot surgery, Olsen had to leave Sunday after aggravating the injury. He played only 21 snaps in the contest.
11 of 18
Josh Sitton, OG, Bears
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Sitton suffered a concussion in the second quarter of Sunday's game against the Eagles and didn't return.
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Jacksonville suffered a big loss on defense when Smith left in the second half with a concussion. Arizona would the game with a field goal at the end.
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Trufant left Sunday's game after colliding with safety Keanu Neal and later ruled out with a concussion.
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The Bucs suffered a tough injury on defense when Ward left with a concussion.
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Williams left Sunday's game with a shoulder injury and was carted off. Kenyan Drake got more playing time in his place.
16 of 18
Mike Williams, WR, Chargers
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LA's rookie wideout left Thursday's game with a knee injury. The Chargers initially feared an ACL injury, but now the team thinks it could be a bone bruise.
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Seattle's No. 2 tight left Sunday's game with a concussion and didn't return.
18 of 18
Derek Wolfe, DE, Broncos
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Wolfe had injury issues earlier this season, and left Sunday's game with a neck injury. He didn't return after getting hurt.